PL HCL
Pyridoxal hydrochloride
CAS: 65-22-5
Molecular Formula: C8H10ClNO3
PL HCL - Names and Identifiers
| Name | Pyridoxal hydrochloride |
| Synonyms | PL HCL TIMTEC-BB SBB000425 PYRIDOXAL HYDROCHLORIDE Pyridoxal hydrochloride Pyridoxal hydrochloride(PLC) PYRIDOXAL HYDROCHLORIDE SUITABLE FOR PYRIDOXAL HCL SIGMA GRADE CRYSTALLIN pyridoxal hcl sigma grade crystalline 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehydhydrochloride |
| CAS | 65-22-5 |
| EINECS | 200-602-5 |
| InChI | InChI=1/C8H9NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,4,10,12H,3H2,1H3;1H |
| InChIKey | FCHXJFJNDJXENQ-UHFFFAOYSA-N |
PL HCL - Physico-chemical Properties
| Molecular Formula | C8H10ClNO3 |
| Molar Mass | 203.62 |
| Melting Point | 173°C (dec.)(lit.) |
| Boling Point | 412.8°C at 760 mmHg |
| Flash Point | 203.5°C |
| Water Solubility | Soluble in water and ethanol. |
| Solubility | Easily soluble in water (1:2), slightly soluble in ethanol (1:60 |
| Vapor Presure | 1.48E-07mmHg at 25°C |
| Appearance | grayish white powder |
| Color | White |
| Merck | 14,7978 |
| BRN | 3656994 |
| Storage Condition | 2-8°C |
| Sensitive | Hygroscopic |
| MDL | MFCD00012809 |
| Physical and Chemical Properties | White crystals. Mp165 C (decomposition), the maximum absorption at 292.5nm wavelength. Soluble in water (1:2), slightly soluble in ethanol (1:60), can be reduced to pyridoxine. |
PL HCL - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S22 - Do not breathe dust. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 2 |
| RTECS | UV1225000 |
| FLUKA BRAND F CODES | 8 |
| TSCA | Yes |
| HS Code | 29362500 |
PL HCL - Reference
| Reference Show more | 1. [IF=5.279] Hao Gong et al."Determination and Comparison of 4′-O-Methylpyridoxine Analogues in Ginkgo biloba Seeds at Different Growth Stages."J Agr Food Chem. 2018;66(30):7916–7922 |
PL HCL - Introduction
Used for labeling and detecting the following substances at the picomolar level (10-12 moles): amino acids, coenzymes and cofactors, pyridoxal phosphate and vitamin B6.
Last Update：2022-10-16 17:27:43
PL HCL - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | pyridoxal (PL) is one of the components of vitamin B6. It is an aldehyde obtained by the oxidation of pyridoxine. It is unstable in neutral and alkaline, and is prone to photolysis. It has an influence on the growth of Streptococcus lactis (Streptococcus lactis), and its effect is thousands of times greater than that of pyridoxine, which is a substance that restores the action of tyrosine debulking enzyme, it was discovered in 1942 from an extract of an organ. In vivo role is the formation of pyridoxal phosphate. It has the function of many enzymes as coenzymes. Therefore, not only its own in the field of medicine, biology has been widely studied and used, and its related products have also been studied in depth. Pyridoxal hydrochloride is the salt form of pyridoxal. |
| Application | pyridoxal hydrochloride can be used to prepare pyridoxal phosphate (PLP). Pyridoxal phosphate is white crystal, chemical name 2-methyl -3-hydroxy -4-formaldehyde -5-hydroxymethyl pyridyl phosphate, is the coenzyme of transaminase and decarboxylase in amino acid metabolism, can promote glutamic acid decarboxylation, enhance the production of gamma-aminobutyric acid, the latter is a neurotransmitter. It is clinically used in the treatment of Parkinson's syndrome drugs, promote transamination of transaminases to increase the content of dopamine in the body. In addition, it can also catalyze a variety of reactions, there are common α-amino acids and α-keto acid transamination and α-amino acid decarboxylation. |
| synthesis method | to a 1 L flask, add 400g of deionized water and 50g of pyridoxine hydrochloride, stir and dissolve uniformly at room temperature, the temperature is raised to 45 ° C., and a mixed solution of 22g of newly prepared manganese sulfate and 46g of potassium permanganate is added in batches, which is divided into 3 times in total, the addition amount of each batch is evenly divided, the addition is completed in 1 hour, and the temperature is raised to 60 ° C. Within 15 minutes. Pyridoxine was completely oxidized and the reaction was completed. The yield of pyridoxal was 94%. |
| Use | biochemical and pharmaceutical research, used as a nutritional agent. in the detection of labeled amino acids and their picomolar amounts, Coenzyme and cofactors: vitamin B6, pyridoxal phosphate used for labeling and at the picomolar level (10-12 molar) the following substances were tested: amino acids, coenzymes and cofactors, pyridoxal phosphate and vitamin B6 |
| production method | vitamin B6 reacts with hydroxylamine hydrochloride to form pyridoxaloxime, which is then prepared by reacting with silver nitrite. |
Last Update：2024-04-09 15:16:52
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Product Name: Pyridoxal hydrochloride Request for quotationCAS: 65-22-5
Tel: +86-17551318830
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QQ: 3785839865
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Product Name: Pyridoxal hydrochloride Request for quotationCAS: 65-22-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Multiple SpecificationsSpot supply
Product Name: Pyridoxal hydrochloride Visit Supplier Webpage Request for quotationCAS: 65-22-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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